Buy Malirid 45 mg (Primaquine) – High‑Dose Radical Cure & Transmission Blocking

Malirid 45 mg contains primaquine phosphate (45 mg base), a potent antimalarial used for radical cure of vivax/ovale malaria and single‑dose gametocyte clearance in falciparum malaria where resistance is an issue, especially in low‑transmission and Southeast Asian regions ([turn0search4], [turn0search18], [turn0search1]).

How It Works

As an 8‑aminoquinoline, primaquine eradicates dormant liver hypnozoites to prevent relapse and rapidly clears mature gametocytes of P. falciparum, helping to stop transmission ([turn0search18], [turn0search20]).

Uses & Benefits

• High‑dose (45 mg) single dose used as a gametocytocide following blood-stage antimalarial therapy in areas with artemisinin resistance ([turn0search18]).
• Prevents relapse of vivax and ovale malaria post‑blood treatment.
• Supports malaria elimination efforts by blocking transmission.

Dosage & Administration

• Adult high‑dose regimen: 45 mg base (≈78.9 mg salt) as a single dose following acute therapy, recommended in low‑transmission or resistant‑strain regions under WHO guidance ([turn0search18], [turn0search1]).
• For relapse prevention: 30 mg base/day for 14 days (or 45 mg once weekly × 8 weeks for G6PD‑intermediate individuals) ([turn0search1], [turn0search3], [turn0search14]).
• Must be supervised by a healthcare professional. Take with food to reduce stomach upset ([turn0search8], [turn0search5]).

Side Effects & Warnings

• Common: nausea, vomiting, stomach cramps, headache, dizziness, fatigue, abdominal discomfort ([turn0search4], [turn0search20]).
• Serious: hemolytic anemia in G6PD deficiency; must test before administration. Methemoglobinemia may occur occasionally ([turn0search4], [turn0search18]).
• Patients with heart disease or renal failure need closer monitoring ([turn0search4]).

Precautions & Interactions

• Contraindicated if G6PD status is unknown or deficient due to risk of severe hemolysis ([turn0search4], [turn0search1]).
• Use with caution in pregnancy and breastfeeding—benefit must outweigh risk and infant G6PD status known ([turn0search4], [turn0search20]).
• Inform your healthcare provider of all medications, especially QT‑prolonging drugs or CYP3A4 inhibitors ([turn0search5]).

Worldwide Shipping

Available with discreet global delivery and tracking. Prescription required. Delivery typically within 6–15 business days.

📌 Frequently Asked Questions (FAQs)

1. When is Malirid 45 mg used?

Used as single-dose gametocytocide following blood-stage treatment for P. falciparum in resistant regions; also used for radical cure of vivax/ovale malaria when higher doses are necessary ([turn0search18], [turn0search1]).

2. How should it be taken?

Take 45 mg base (78.9 mg tablet) once with food under medical supervision; follow-up blood tests recommended ([turn0search8], [turn0search5]).

3. What are side effects?

Generally mild: nausea, cramps, headache, dizziness. Risk of hemolysis in G6PD deficiency or bluish discoloration (methemoglobinemia)—monitor closely ([turn0search4], [turn0search20]).

4. Is G6PD testing required?

Yes—mandatory before use, as severe anemia can occur in deficiency. Weekly regimen may be used in intermediate deficiency only under supervision ([turn0search1], [turn0search14]).

5. Can it be used during pregnancy or while breastfeeding?

Not recommended in pregnancy. Breastfeeding allowed only if infant is confirmed G6PD-normal. Consult a physician before use ([turn0search4], [turn0search20]).