Description
Midotab 5 mg (Midodrine) – Effective Treatment for Orthostatic Hypotension
Midotab 5 mg tablet contains midodrine hydrochloride, an oral α₁‑adrenergic agonist used to treat symptomatic orthostatic hypotension—helping manage dizziness or fainting when standing.
Key Benefits:
- Relieves dizziness, lightheadedness, and faintness upon standing
- Elevates blood pressure without significantly affecting heart rate
- Helps improve daily activity tolerance in autonomic dysfunction patients
How It Works
Midodrine is a prodrug converted to desglymidodrine, a selective α₁‑agonist. It constricts arterioles and veins, increasing vascular resistance and boosting standing blood pressure.
Dosage & Administration
Adults typically take 2.5–10 mg orally, three times daily during daytime hours while upright. The recommended usual dose is 10 mg TID at about 4‑hour intervals, with the last dose at least 4 hours before bedtime to reduce supine hypertension risk.
Possible Side Effects
- Supine hypertension (notably when lying down)—requires blood pressure monitoring
- Goosebumps, scalp tingling, chills, headache, flushing
- Urinary retention or urgency, nausea, rash, itching
Precautions & Interactions
- Contraindicated in severe heart disease, acute renal disease, CHF, pheochromocytoma, thyrotoxicosis, urinary retention, or narrow‑angle glaucoma.
- Monitor supine and standing BP during initiation—especially early doses.
- Avoid taking the dose less than four hours before lying down.
- Caution when combined with other antihypertensives, cardiac drugs, or pressor agents.
Why Choose Midotab?
- Available in India as a cost-effective midodrine brand by J B Chemicals & Pharma
- Clinically proven oral option for patients with debilitating orthostatic hypotension
- Convenient daytime dosing regimen tailored to upright symptom relief
Frequently Asked Questions (FAQs)
1. What is Midotab 5 mg used for?
It is prescribed to treat orthostatic hypotension—particularly symptoms of dizziness or fainting after standing.
2. How quickly does it work?
Effects begin within ~30 minutes; duration roughly 2–6 hours.
3. What should I do if I miss a dose?
Take it as soon as remembered, provided you can stay upright for a few hours. Skip if bedtime is near. Do not double dose.
4. Can I lie down after taking it?
Ideally avoid lying down within 4 hours of dosing to minimize risk of supine hypertension.
5. Is blood pressure monitoring required?
Yes—both supine and standing pressures should be checked periodically, especially during dose titration.
