Lanoxin 0.25 mg (Digoxin)
Lanoxin 0.25 mg contains digoxin, a cardiac glycoside used for rate control in atrial fibrillation and for symptomatic management of selected patients with heart failure. Digoxin increases cardiac contractility and exerts parasympathetic effects that slow atrioventricular conduction. It is a prescription medicine with a narrow therapeutic index and requires careful dosing and monitoring.
Product introduction
Digoxin has been used for decades in cardiology. The 0.25 mg tablet is a commonly available strength useful for maintenance dosing. Because digoxin levels are influenced by renal function, body size, age and interacting medications, individualised dosing and periodic blood testing (serum drug level, electrolytes, renal function) are essential to safe use.
Uses of Lanoxin 0.25 mg (Digoxin)
Typical clinical uses include:
- Rate control in atrial fibrillation (particularly in patients with heart failure or reduced exercise tolerance)
- Symptomatic management of heart failure with reduced ejection fraction as an adjunct to other guideline-directed therapies
- Occasionally used for certain supraventricular tachyarrhythmias under specialist direction
Note: Exact role and dosing depend on comorbidities, renal function and concomitant medicines—follow your cardiologist’s instructions.
Benefits of Lanoxin 0.25 mg (Digoxin)
- Improved symptoms: can reduce breathlessness and fatigue in some heart-failure patients.
- Effective rate control: helps slow ventricular rate in atrial fibrillation, especially at rest.
- Oral once-daily dosing: convenient maintenance therapy when indicated.
Side effects of Lanoxin 0.25 mg (Digoxin)
Digoxin has a narrow therapeutic window—signs of toxicity may appear even at near-therapeutic concentrations. Monitor closely.
Common side effects
- Nausea, vomiting, abdominal discomfort
- Loss of appetite
- Fatigue, dizziness
- Visual disturbances (blurred vision, yellow-green halos)
- Bradycardia (slow heart rate)
Serious risks: life-threatening arrhythmias, severe bradycardia, or advanced heart block. Seek immediate medical care for fainting, severe dizziness, chest pain, palpitations, or pronounced visual changes.
How to use Lanoxin 0.25 mg (Digoxin)
- Take exactly as prescribed by your clinician. Typical maintenance doses range from 0.125 mg to 0.25 mg once daily depending on individual factors; lower doses are commonly used in elderly patients or those with renal impairment.
- Loading (digitalization) regimens may be used in hospital settings—do not attempt without medical supervision.
- Swallow tablets whole with water; take at the same time each day.
- Do not miss scheduled blood tests—serum digoxin level, renal function and electrolytes (potassium, magnesium, calcium) are key to safe therapy.
- If a dose is missed, follow your prescriber’s advice—do not double doses.
How Lanoxin works
Digoxin inhibits the sodium–potassium ATPase pump in cardiac myocytes, increasing intracellular calcium and thereby enhancing contractility. It also increases vagal tone which slows conduction through the AV node—useful for controlling ventricular rate in atrial fibrillation.
Safety advice
| Pregnancy / Breastfeeding | Use only if clearly needed and under specialist supervision. Discuss risks and benefits with your clinician. |
| Renal impairment | Digoxin is renally cleared—dose reduction and closer monitoring are required in reduced kidney function. |
| Electrolytes | Low potassium, low magnesium or high calcium increase digoxin toxicity risk—monitor and correct electrolytes promptly. |
| Drug interactions | Many drugs alter digoxin levels or increase its arrhythmogenic potential (e.g., amiodarone, verapamil, diltiazem, quinidine, macrolide antibiotics, certain antivirals, some calcium channel blockers, and diuretics that cause hypokalaemia). Always provide a full medication list to your clinician. |
| Arrhythmia risk | Report palpitations, syncope, new chest pain or extreme breathlessness immediately—digoxin can both treat and provoke arrhythmias if levels are inappropriate. |
| Driving / machinery | Dizziness or visual changes may occur—avoid hazardous tasks until you know how digoxin affects you. |
What if you forget a dose?
- If you miss one dose, take it as soon as you remember the same day unless your clinician has advised otherwise.
- Do not take two doses at the same time to make up for a missed dose. If multiple doses are missed, contact your clinician.
All substitutes
Therapy alternatives depend on the indication:
- For rate control in AF: beta-blockers (e.g., metoprolol), non-dihydropyridine calcium channel blockers (e.g., diltiazem, verapamil) where appropriate
- For heart failure: guideline-directed medical therapy including ACE inhibitors/ARBs/ARNI, beta-blockers, MRAs, SGLT2 inhibitors—digoxin may be adjunctive in selected patients
Quick tips
- Keep regular blood tests for digoxin level, renal function and electrolytes—especially after dose changes or if you start/stop other medicines.
- Carry a medicines list noting you take digoxin and emergency contact details.
- Report signs of toxicity (nausea, vomiting, visual changes, confusion, dizziness, palpitations) promptly.
- Store tablets at room temperature away from moisture and heat; keep out of reach of children.
Fact Box
| Generic name | Digoxin |
| Brand | Lanoxin 0.25 mg |
| Drug class | Cardiac glycoside |
| Form | Oral tablet (0.25 mg) |
| Typical maintenance dose | 0.125–0.25 mg once daily (individualised; lower doses often used in elderly or renal impairment) |
| Prescription | Required — specialist/physician supervision and monitoring |
Patient concerns
Will Lanoxin cure my heart condition? No — digoxin helps control symptoms and heart rate in selected patients but is usually part of a broader, long-term treatment plan. Discuss goals and expected outcomes with your cardiologist.
How soon will I notice effects? Rate control effects can occur within hours; symptomatic improvement in heart failure may take longer and depends on overall treatment.
User feedback
Many patients appreciate improved symptom control and better heart-rate stability with appropriate digoxin dosing. Concerns about side effects are usually managed by careful monitoring and dose adjustment.
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FAQs
Can I take Lanoxin with diuretics?
Some diuretics (especially loop and thiazide diuretics) can lower potassium and increase risk of digoxin toxicity. Use with caution and under close monitoring—your clinician may adjust doses and schedule blood tests.
Is there an antidote for digoxin toxicity?
Yes — digoxin-specific antibody fragments (digoxin immune Fab) are used in severe, life-threatening poisoning; such treatment is given in hospital. Mild toxicity is managed by stopping digoxin, correcting electrolytes and supportive care. Seek urgent care for suspected toxicity.
How should I store Lanoxin?
Store at room temperature away from moisture and heat. Keep out of reach of children and do not use after the expiry date.
Related products
- Beta-blockers (metoprolol, bisoprolol)
- Non-dihydropyridine calcium channel blockers (diltiazem, verapamil)
- Heart-failure guideline therapies (ACEi/ARB/ARNI, MRAs, SGLT2 inhibitors)
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Disclaimer:
This article is for educational purposes only and does not replace professional medical advice. Lanoxin (digoxin) must be prescribed and monitored by qualified clinicians. Do not change or stop therapy without medical advice.
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For ordering or prescription verification use live chat or our contact page. For medical concerns contact your treating clinician immediately.
Lab tests offered by us
- Serum digoxin level (trough), renal function tests (creatinine, eGFR)
- Electrolytes (potassium, magnesium, calcium)
- ECG if arrhythmia suspected
Additional offers
Prescription coordination and cardiology referrals available on request. Use code GLOBAL10 where eligible for first-order discounts.
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