Apismart 5 mg (Apixaban)
Apismart 5 mg contains apixaban, an oral direct factor Xa inhibitor (direct oral anticoagulant, DOAC) used to prevent and treat thromboembolic disorders. Apixaban reduces clot formation by selectively inhibiting factor Xa in the coagulation cascade and is commonly prescribed for stroke prevention in non-valvular atrial fibrillation (AF) and for treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE).
Apismart is a prescription anticoagulant. Use requires clinician assessment because of bleeding risk, drug interactions and the need to individualise dosing in some clinical situations.
Product introduction
Apixaban is a rapid-onset oral anticoagulant that does not require routine laboratory monitoring of anticoagulant effect in most patients. The 5 mg tablet is a standard maintenance dose for many indications; dose adjustments are indicated in certain patients (e.g., renal impairment, low body weight, advanced age, or concomitant interacting medicines).
Uses of Apismart 5 mg (Apixaban)
Common indications include:
- Stroke prevention in non-valvular atrial fibrillation (AF)
- Treatment of acute DVT and PE (often after initial lead-in dosing as per guideline)
- Secondary prevention of recurrent DVT and PE
- Venous thromboembolism (VTE) prophylaxis in selected surgical patients (where indicated)
Note: Indications, dosing regimens and duration vary by clinical context—follow your prescriber’s instructions and local guidelines.
Benefits of Apismart 5 mg
- Effective anticoagulation: reduces stroke risk in AF and prevents recurrence of VTE.
- Oral once- or twice-daily dosing: fixed dosing without routine INR monitoring in most patients.
- Lower intracranial bleeding risk: compared with some vitamin K antagonist strategies in many trials.
- Rapid onset and offset: offers predictable anticoagulant effect and flexibility around procedures when planned appropriately by clinicians.
Recommended dosing
Common adult dosing (examples — individualise per clinician):
- Atrial fibrillation (stroke prevention): 5 mg twice daily. Use reduced dose (2.5 mg twice daily) if a patient meets two or more of the following: age ≥80 years, body weight ≤60 kg, serum creatinine ≥1.5 mg/dL (or other local renal criteria) — follow local product labeling.
- Acute DVT/PE treatment: when used as single-drug therapy, many regimens start with higher-intensity apixaban (e.g., 10 mg twice daily for 7 days) then 5 mg twice daily—follow local guidance and prescriber instructions.
- Secondary prevention: doses and duration vary by risk—follow prescriber advice.
Do not change dose unless instructed. Take with or without food, but take at the same times each day for consistent effect.
Side effects of Apismart 5 mg (Apixaban)
The most important risk is bleeding. While many patients tolerate apixaban well, any unexplained bleeding should be assessed promptly.
Common side effects
- Bruising or minor bleeding (gum bleed, nosebleed)
- Increased menstrual bleeding
- Minor gastrointestinal discomfort
Serious risks: major bleeding (gastrointestinal bleeding, intracranial hemorrhage), bleeding requiring transfusion, and rarely hypersensitivity reactions. Seek immediate medical attention for severe bleeding, black/tarry stools, vomiting blood, sudden severe headache or neurological changes, unexplained fainting or heavy bleeding.
How to use Apismart 5 mg
- Take exactly as prescribed by your clinician.
- For most maintenance indications the usual regimen is 5 mg twice daily—confirm with your prescriber.
- Swallow tablets whole with water; do not crush unless instructed.
- If you are scheduled for an invasive procedure, do not stop or alter therapy without clinician advice—timing of interruption depends on bleeding risk, renal function and the procedure.
- If vomiting occurs soon after dosing, contact your clinician for advice.
How Apismart works
Apixaban selectively and reversibly inhibits factor Xa, reducing thrombin generation and thrombus formation. By preventing clot propagation, it lowers the risk of stroke in AF and treats or prevents venous thromboembolism.
Safety advice
| Bleeding risk | Inform all healthcare providers and dental teams that you take apixaban. Avoid NSAIDs and other medications that increase bleeding risk unless approved by your clinician. Use caution with activities that increase injury risk. |
| Renal impairment | Dose adjustment or alternative therapy may be required for severe renal dysfunction—clinician assessment needed. |
| Liver disease | Use caution in moderate–severe hepatic impairment; contraindicated in severe hepatic disease with coagulopathy—follow local product labeling. |
| Drug interactions | Avoid strong combined P-gp and CYP3A4 inhibitors (e.g., certain azole antifungals, ritonavir) or inducers (e.g., rifampicin, certain anticonvulsants) unless specialist guidance is provided. Always provide an up-to-date medicines list to your prescriber or pharmacist. |
| Pregnancy & breastfeeding | Apixaban is generally avoided in pregnancy; discuss risks with your clinician. Breastfeeding decisions should be made with specialist advice. |
| Reversal | For life-threatening bleeding, specific reversal agents or pro-hemostatic measures may be used by hospitals—seek emergency care immediately for serious bleeding. |
What if you forget a dose?
- If you miss a dose, take it as soon as you remember on the same day and continue the usual schedule.
- Do not double doses to make up for a missed one.
- If you miss more than one dose, contact your clinician for instructions.
All substitutes
Other oral anticoagulants and alternatives (selection depends on indication):
- Other DOACs: rivaroxaban, dabigatran, edoxaban (choice based on indication and patient factors)
- Warfarin (vitamin K antagonist) — requires INR monitoring and dietary considerations
- Parenteral anticoagulants (e.g., low-molecular-weight heparin) for certain clinical needs
Quick tips
- Carry an anticoagulant alert card or wear medical identification that states you are taking apixaban.
- Tell your surgeon, dentist or emergency clinician you take apixaban before any procedure.
- Avoid over-the-counter NSAIDs and herbal supplements that increase bleeding risk unless cleared by your clinician.
- Discuss vaccination timing, pregnancy plans and travel with your clinician if you are on long-term anticoagulation.
Fact Box
| Generic name | Apixaban |
| Brand | Apismart 5 mg |
| Drug class | Direct Factor Xa inhibitor (DOAC) |
| Form | Oral tablet (5 mg) |
| Typical dosing | 5 mg twice daily for many maintenance indications (dose adjustments per prescriber and local labeling) |
| Prescription | Required — anticoagulation specialist or prescribing clinician oversight recommended |
Patient concerns
Will Apismart stop all clots? Apixaban reduces the risk of clot formation but does not eliminate it entirely. Effectiveness depends on correct dosing, adherence and individual risk factors.
Will I need routine blood tests? Routine measurement of anticoagulant effect is not required for most DOAC users. However, clinicians may check renal and liver function periodically and before procedures.
User feedback
Many patients appreciate the convenience of fixed-dose oral anticoagulation without routine INR monitoring compared with warfarin. The main patient concern is bleeding risk, which is usually manageable with education and clinician follow-up.
FAQs
Can I take Apismart with aspirin?
Combining apixaban with antiplatelet agents (e.g., aspirin) increases bleeding risk and is only done when strongly indicated (e.g., recent coronary stent). Follow specialist advice—do not combine without medical supervision.
Can Apismart be used in kidney disease?
Use depends on degree of renal impairment. Dose adjustments or alternative agents may be required—discuss with your prescriber and check renal function before and during therapy as recommended.
How should I store Apismart?
Store at room temperature away from moisture and heat. Keep out of reach of children and do not use past the expiry date.
Related products
- Rivaroxaban, Dabigatran, Edoxaban (other DOACs)
- Warfarin (vitamin K antagonist)
- Low-molecular-weight heparin (LMWH)
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Disclaimer:
This article is for educational purposes only and does not replace personalised medical advice. Apismart (apixaban) must be prescribed and monitored by a qualified clinician. Do not change or stop anticoagulation without discussing it with your healthcare provider.
Marketer details
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In case of any issues, contact us
For order or prescription verification use live chat or our contact page. For medical emergencies (severe bleeding, stroke symptoms) call emergency services immediately.
Lab tests offered by us
- Renal function (serum creatinine, eGFR)
- Liver function tests
- Coagulation panel if clinically indicated
Additional offers
Anticoagulation counselling, prescription coordination and treatment support available on request. Use code GLOBAL10 where eligible for first-order discounts.
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