Silectone 100 mg (Spironolactone) – Potassium‑Sparing Diuretic for Hypertension, Heart Failure & Edema

Silectone 100 mg contains spironolactone, a potassium‑sparing diuretic used to treat swelling (edema), heart failure, hypertension, low potassium, and primary hyperaldosteronism. It’s also used off-label to address androgen-related skin conditions. 

Key Benefits:

• Reduces excess fluid retention and swelling
• Helps lower high blood pressure
• Used in heart failure to reduce mortality and hospitalization
• Manages elevated aldosterone levels in Conn’s syndrome

How It Works

Spironolactone blocks aldosterone receptors and inhibits excess sodium reabsorption while conserving potassium—reducing fluid volume without hypokalemia risk. Its antiandrogenic activity also explains use in hormone-related skin conditions. 

Recommended Dosage

Prescribed at varying doses—100 mg once daily for edema, hypertension, or hyperaldosteronism. Dosage adjustment required for kidney or liver impairment and for elderly. Take with food and maintain hydration. 

Possible Side Effects

• Nausea, vomiting, diarrhea, stomach cramps, dizziness, drowsiness, leg cramps 
• Breast tenderness, gynecomastia in men, menstrual irregularities in women
• Electrolyte disturbances: hyperkalemia, dehydration, low blood pressure 
• Poor kidney function, confusion, blurred vision, dehydration signs may indicate serious effects 

Precautions & Interactions

• Contraindicated in hyperkalemia, severe kidney disease, Addison’s disease 
• Avoid potassium supplements or high potassium foods and salt substitutes
• Use caution if combining with ACE inhibitors, ARBs, NSAIDs, or trimethoprim 
• Avoid alcohol and rise slowly to prevent orthostatic hypotension
• Consult physician before use during pregnancy or breastfeeding due to antiandrogenic effects 

Why Choose Silectone?

• Manufactured by Johnlee Pharmaceuticals—a trusted brand in cardiovascular care 
• Effective and affordable generic alternative to Aldactone
• Addresses multiple indications like hypertension, edema, hyperaldosteronism, and heart failure

Frequently Asked Questions (FAQs)

1. What is Silectone 100 mg used for?

It’s used to manage hypertension, edema from heart/liver/kidney issues, heart failure, elevated aldosterone, and low potassium levels.

2. How long until results appear?

Diuresis often starts within hours; blood pressure and edema control may take several days of consistent use. 

3. What if I miss a dose?

Take it as soon as remembered unless it’s near your next dose—then skip. Never double up.

4. What should I avoid while taking Silectone?

Avoid potassium supplements, salt substitutes, high-potassium foods, and alcohol; these increase risk of hyperkalemia or hypotension.

5. Is monitoring required?

Yes—especially for kidney function, serum potassium/sodium, and signs of dehydration or electrolyte imbalance.