Buy Ismo 10 mg (Isosorbide Mononitrate) – Immediate‑Release Angina Prevention

Ismo 10 mg tablets contain isosorbide-5-mononitrate, an oral nitrate used to prevent angina pectoris and support heart function in congestive failure when standard therapies are inadequate. 

How It Works

Isosorbide mononitrate converts to nitric oxide, relaxing venous and arterial smooth muscle—reducing cardiac preload and afterload to improve blood flow and reduce chest pain. 

Indications & Benefits

• Prevention of stable angina due to coronary artery disease. 
• Adjunct therapy in heart failure not adequately responding to glycosides/diuretics. 

Dosage & Administration

• Starter regimen: 10 mg once daily for 2 days, then 20 mg daily in divided doses. 
• Maintenance: 20 mg twice daily, 7 hours apart (e.g., waking + mid-day) to avoid tolerance. 
• Lower initial dose (5 mg twice daily) for small or elderly patients; gradually titrate. 
• Avoid abrupt discontinuation—taper with physician guidance. 

Common Side Effects & Safety

• Very common: headaches (primary cause of discontinuation), facial flushing, dizziness. 
• Others: nausea, weakness, low blood pressure, palpitations. Serious issues like syncope are rare. 

⚠️ Precautions & Interactions

• Do not use with PDE‑5 inhibitors (e.g., sildenafil, tadalafil) due to risk of severe hypotension. 
• Avoid combining with other vasodilators or antihypertensives without monitoring. 
• Rise slowly to avoid orthostatic hypotension. Do not drive or drink alcohol if dizzy. 
• Monitor carefully in patients with renal/hepatic impairment; no significant dose adjustments needed. 

Global Availability & Prescription Info

Ismo 10 mg is a prescription-only immediate-release nitrate available globally, commonly under brand names like Ismo and Monoket. Use requires regular supervision in cardiovascular conditions. 

📌 Frequently Asked Questions (FAQs)

1. What is Ismo 10 mg used for?

It’s used to prevent episodes of angina and support management of heart failure as adjunct therapy in select cases. 

2. How and when do I take it?

Begin with 10 mg once daily for two days, then increase to 20 mg per day given in two doses, 7 hours apart—for example at wake-up and mid-afternoon. 

3. What side effects are common?

Headache is very common and often indicates efficacy. Other effects include flushing, dizziness, nausea, and fatigue. These often diminish over time. 

4. Can I stop it suddenly?

No—stop it only under medical advice. Abrupt withdrawal may cause rebound angina or worsening heart condition. 

5. Are there any critical interactions?

Avoid using PDE‑5 inhibitors (Viagra, Cialis) with Ismo due to risk of very low blood pressure. Alcohol and other vasodilators also increase risk.