Buy Ranx 1000 mg (Ranolazine ER) – Extended‑Release Treatment for Chronic Angina

Ranx 1000 mg, by Unichem Laboratories, contains ranolazine, an extended-release medication used alongside other cardiovascular therapies to manage chronic stable angina.

How It Works

Ranolazine inhibits late inward sodium current (I_Na) and reduces intracellular calcium overload in cardiac cells, easing myocardial tension and improving blood flow without significantly reducing heart rate or blood pressure. 

Indications & Benefits

• Approved for chronic stable angina not adequately controlled by other therapies. 
• Can be combined with beta-blockers, calcium channel blockers, nitrates, ACE inhibitors, antiplatelets, and lipid-lowering agents. 
• Shown to improve exercise tolerance and reduce anginal episodes. 

📌 Dosage & Administration

• Start: 500 mg twice daily with or without food. Increase to 1000 mg twice daily based on symptoms and tolerance. 
• Do not exceed 1000 mg twice daily. Tablets must not be crushed or chewed. 
• If a dose is missed, take the next one at the usual time. Never double doses. 

Side Effects & Safety

• Common: dizziness, headache, constipation, nausea, dry mouth. 
• QT prolongation: dose-related effect—monitor if combined with other QT-prolonging medications or in liver impairment. 
• Use caution in elderly, patients under 60 kg, or with preexisting renal/liver disease. 

⚠️ Precautions & Drug Interactions

• Contraindicated in hepatic cirrhosis and concurrent use of strong CYP3A inhibitors (e.g., ketoconazole, clarithromycin) or inducers (e.g., rifampin, carbamazepine). 
• Reduce max dose to 500 mg twice daily when used with moderate CYP3A inhibitors like verapamil, diltiazem or erythromycin.
• Monitor renal function closely; discontinue if acute renal failure develops. 
• Potential interactions requiring dosage adjustments: metformin, digoxin, certain antidepressants, immunosuppressants, and statins. ([turn0search3], [turn0search10])
• Avoid grapefruit juice—it inhibits CYP3A and increases exposure. Do not operate vehicles if dizziness occurs. 

Global Availability & Prescription Info

Ranx 1000 mg is prescription-only and supplied globally via licensed pharmacies. Manufactured by Unichem Laboratories (India). Requires supervised use in conjunction with other cardiovascular therapies. 

📌 Frequently Asked Questions (FAQs)

1. What is Ranx 1000 mg used for?

It’s used to relieve chronic stable angina symptoms in patients whose chest pain isn’t fully controlled by other treatments.

2. How quickly does it work?

Improvement in angina symptoms may be noticed within days; full effect often takes longer and depends on dose ramp-up and combination therapies. 

3. What side effects might I experience?

Expect dizziness, headache, dry mouth, nausea, or constipation. QT prolongation is possible—cease if experiencing fainting or palpitations.

4. Can I take other heart medicines with Ranx?

Yes. It’s typically used with beta-blockers, nitrates, or calcium-channel blockers—but avoid certain CYP3A inhibitors/inducers. Consult your doctor before combining. 

5. What should I do if I miss a dose?

Take it as soon as you remember unless it’s time for the next dose. Do not double the dose. Continue your regular schedule.