Amoxyclav 375 mg (Amoxicillin/Clavulanic Acid)

Amoxyclav 375 mg (Amoxicillin/Clavulanic Acid)

Amoxyclav 375 mg contains a combination of amoxicillin (a penicillin-class antibiotic) and clavulanic acid (a beta-lactamase inhibitor). This combination enhances the effectiveness of amoxicillin against bacteria that would otherwise be resistant. It is widely used for respiratory tract infections, ENT infections, urinary tract infections, skin & soft tissue infections, and some dental infections.

The 375 mg strength is commonly used for mild to moderate infections and provides balanced antibiotic coverage for outpatient treatment.

Product introduction

Amoxyclav combines a potent antibiotic with clavulanate, which blocks beta-lactamase enzymes produced by resistant bacteria. This allows amoxicillin to remain effective against organisms that typically break down penicillins. It offers wide coverage across respiratory, ENT, urinary, and dental infections, making it a first-line choice for many conditions.

Always use Amoxyclav under medical guidance to avoid resistance and ensure safe usage.

Uses of Amoxyclav 375 mg (Amoxicillin/Clavulanic Acid)

Amoxyclav 375 mg is prescribed for bacterial infections including:

• Respiratory tract infections:
  • Bronchitis
  • Tonsillitis & pharyngitis
  • Community-acquired pneumonia (mild–moderate)
• ENT infections:
  • Sinusitis
  • Otitis media
• Urinary tract infections (UTIs)
• Skin & soft-tissue infections
• Dental infections
• Some gastrointestinal bacterial infections

Note: Amoxyclav has no effect on viral infections like the common cold or flu.

Benefits of Amoxyclav 375 mg

Key advantages include:

• Extended antibacterial coverage due to clavulanic acid.
• Effective against resistant bacteria producing beta-lactamase.
• Well tolerated in most patients.
• Widely used as a first-line therapy for ENT and respiratory infections.
• Useful for mixed infections involving multiple organisms.

In Treatment of Worm infections

Important: Amoxyclav is not used for treatment of worm or parasitic infections. This section is included only to maintain consistent page structure.

Side effects of Amoxyclav 375 mg

Most side effects are mild and improve with continued use.

Common side effects

• Diarrhoea
• Nausea or vomiting
• Stomach discomfort
• Skin rash
• Headache

Serious but rare: liver injury, allergic reactions, severe diarrhoea (C. difficile), jaundice, and severe skin reactions like Stevens-Johnson syndrome. Seek urgent care for breathing difficulty, facial swelling, or persistent severe diarrhoea.

How to use Amoxyclav 375 mg

• Take exactly as prescribed by your clinician.
• Typically taken two to three times daily depending on infection type.
• Take with food to reduce stomach upset.
• Swallow the tablet whole with water.
• Complete the full course even if symptoms improve early.

If symptoms do not improve within 48–72 hours, contact your doctor.

How Amoxyclav 375 mg works

Amoxicillin kills susceptible bacteria by inhibiting cell-wall synthesis. Clavulanic acid prevents destruction of amoxicillin by beta-lactamase enzymes. Together, they provide broader and more reliable antibacterial activity.

Safety advice

What if you forget to take Amoxyclav 375 mg?

If you miss a dose:

• Take it as soon as you remember.
• If it’s almost time for the next dose, skip the missed one.
• Do not double the dose.

All substitutes

Alternatives include:

• Augmentin 375 mg
• Amoxicillin 500 mg
• Cefuroxime (Cetil 500 mg)
• Azithromycin 500 mg (for penicillin-allergic patients)

Use only under medical advice.

Quick tips

• Take with food to reduce stomach upset.
• Maintain hydration.
• Stop and report any allergic reactions immediately.
• Store in a cool, dry place.

Fact Box

Patient concerns

Will this treat my sinus infection? Yes, it is commonly prescribed for sinusitis depending on severity.

How long before I feel better? Most patients improve within 48–72 hours.

User feedback

Patients report fast improvement in throat, dental, sinus, and urinary infections. Mild diarrhoea is the most common side effect.

Are you currently taking Amoxyclav 375 mg? Let us know how well it is working for you by taking this survey.

FAQs

Can I stop taking Amoxyclav once I feel better?

No — complete the full course as advised.

Does Amoxyclav cause diarrhoea?

Yes, due to disturbance of gut flora. Persistent diarrhoea requires medical attention.

Can I take probiotics with this medicine?

Yes — probiotics may reduce stomach upset and diarrhoea.

How should I store this medicine?

Store in a cool, dry place away from moisture and sunlight.

Related products

• Cetil 500 mg
• Cephadex 500 mg
• View all antibiotics

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Disclaimer:

This information is for educational purposes only and does not replace medical advice.

References

• Clinical guidelines for penicillin antibiotics
• WHO antimicrobial prescribing references

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Lab tests offered by us

• CBC (Complete Blood Count)
• Liver function test
• Urine culture

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