Arkamin 100 mcg (Clonidine)
Arkamin 100 mcg contains clonidine, a centrally acting alpha-2 adrenergic agonist used for the management of high blood pressure and several specialist indications such as menopausal hot flashes, certain withdrawal syndromes, ADHD (specialist-directed), and autonomic symptoms. Clonidine lowers blood pressure by reducing sympathetic outflow from the brain.
Because of its potent effects on BP and heart rate, Arkamin must be used under medical guidance. Abrupt discontinuation can cause rebound hypertension.
Product introduction
Clonidine is a long-established antihypertensive that reduces peripheral vascular resistance by decreasing central sympathetic activity. The 100 mcg tablet is a common starting and maintenance dose, allowing fine-tuned titration. In certain scenarios, clonidine is used for non-cardiac indications including hypertension crises (oral/IV forms), withdrawal from opioids or benzodiazepines (specialist-directed), and adjunct treatment in ADHD.
Uses of Arkamin 100 mcg (Clonidine)
Clinically approved and specialist uses include:
- Hypertension (high blood pressure) when other therapies are inadequate or unsuitable
- Hypertensive urgency (under medical supervision)
- Management of menopausal hot flashes
- Adjunct in opioid, nicotine or benzodiazepine withdrawal (specialist use)
- ADHD (as part of specialist paediatric treatment plans; region-dependent)
- Tourette’s syndrome (second-line adjunct, clinician-directed)
Note: Clonidine is rarely first-line for hypertension today, but remains useful in resistant cases or specific clinical settings.
Benefits of Arkamin 100 mcg (Clonidine)
- Effective BP reduction: reduces sympathetic drive, lowering heart rate and vascular resistance.
- Useful in resistant hypertension: works via a different mechanism than standard BP medicines.
- Non-hormonal option for hot flashes: can help some patients intolerant to hormonal therapies.
- Reduces withdrawal symptoms: helps manage autonomic hyperactivity in certain withdrawal states.
In other conditions
Note: Indications such as ADHD and withdrawal management require specialist supervision and may vary by country.
Side effects of Arkamin 100 mcg (Clonidine)
Side effects are generally dose-dependent and reflect reduced sympathetic activity.
Common side effects
- Drowsiness, fatigue
- Dry mouth
- Dizziness, lightheadedness
- Constipation
- Lowered heart rate (bradycardia)
Serious risks: severe hypotension, very slow heart rate, fainting, mood changes, and **rebound hypertension** if the medicine is stopped abruptly. Any chest pain, severe headache, blurred vision or collapse requires urgent medical evaluation.
How to use Arkamin 100 mcg (Clonidine)
- Take exactly as prescribed, commonly 100 mcg once or twice daily; doses may be adjusted gradually.
- Do not stop clonidine suddenly — this can cause dangerous spikes in blood pressure.
- Swallow tablets with water; food is optional.
- If used for hypertension, measure BP regularly and follow your clinician’s titration schedule.
- For withdrawal, ADHD or other non-BP indications, follow specialist instructions carefully.
How Arkamin (Clonidine) works
Clonidine stimulates central alpha-2 adrenergic receptors, reducing sympathetic nerve signals to blood vessels and the heart. This lowers heart rate, decreases vascular resistance and reduces blood pressure. It also dampens autonomic hyperactivity, which explains its role in withdrawal syndromes and certain neuropsychiatric uses.
Safety advice
| Pregnancy / Breastfeeding | Use only if prescribed; clonidine crosses the placenta and enters breast milk. Discuss risks and alternatives with your clinician. |
| Heart conditions | Caution in bradycardia, conduction disorders or severe coronary disease. May worsen low heart rate. |
| Alcohol | Avoid alcohol — enhances sedation and BP lowering, increasing fall risk. |
| Mental health | May cause mood changes or depression in some patients; report any behavioural changes. |
| Drug interactions | Caution with beta-blockers, sedatives, opioids, antidepressants and BP-lowering drugs; risk of excessive hypotension or sedation. Stopping beta-blockers before clonidine is risky — clinicians usually taper clonidine first. |
| Driving / operating machinery | Drowsiness and dizziness are common; avoid such activities until effects are known. |
What if you forget to take Arkamin?
- Take the missed dose as soon as you remember unless it is almost time for your next dose.
- Do not double doses.
- If multiple doses are missed, contact your clinician — abrupt withdrawal risks rebound hypertension.
All substitutes
Alternative medicines depend on the condition being treated:
- For hypertension: ACE inhibitors, ARBs, beta-blockers, calcium channel blockers, diuretics.
- For hot flashes: gabapentin, SSRIs/SNRIs (specialist use).
- For withdrawal: buprenorphine/methadone (opioid withdrawal), diazepam/other agents (benzodiazepine tapering) — specialist-managed.
- For ADHD: guanfacine ER, atomoxetine, stimulants — specialist-prescribed.
Choice depends on diagnosis, age, comorbidities and clinician judgement.
Quick tips
- Never stop clonidine suddenly — always taper.
- Stay hydrated and rise slowly to reduce dizziness.
- Track BP at home if prescribed for hypertension.
- Avoid sedating medicines unless approved by your clinician.
- Report slow heartbeat, fainting, chest pain or severe headaches immediately.
Fact Box
| Generic name | Clonidine |
| Brand | Arkamin 100 mcg |
| Drug class | Central alpha-2 adrenergic agonist |
| Form | Oral tablet (100 mcg) |
| Typical dosing | 100–200 mcg/day divided; may increase gradually based on indication |
| Prescription | Required — clinician supervision recommended |
Patient concerns
Will Arkamin cure my high blood pressure? No single medicine cures hypertension; rather, Arkamin helps control BP as part of a long-term treatment plan.
Why do I feel sleepy? Drowsiness is a known effect of clonidine. This may improve over time; if excessive, discuss dose timing or alternatives with your clinician.
User feedback
Patients often report good BP control, reduced hot flashes or reduced withdrawal symptoms, but many note sedation or dry mouth. Consistent dosing and slow tapering are essential to avoid rebound hypertension.
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FAQs
Can I take Arkamin at night?
Yes — many patients take evening doses to reduce daytime drowsiness, but follow your clinician’s schedule.
Is Arkamin addictive?
No, but abrupt discontinuation causes physical rebound (rapid BP rise). Always taper slowly.
Can Arkamin be used in children?
Yes, but only under specialist supervision (e.g., ADHD or Tourette’s). Dosing must be individualized.
How should I store Arkamin?
Store at room temperature away from heat and moisture. Keep out of reach of children and do not use past expiry.
Related products
- Guanfacine (alternate alpha-2 agonist)
- Beta-blockers for hypertension or autonomic symptoms
- SSRIs/SNRIs (hot flashes)
- Withdrawal support medicines (clinician-directed)
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Disclaimer:
This article provides educational information only and does not replace medical advice. Arkamin (clonidine) must be prescribed and monitored by a qualified clinician. Do not self-discontinue — taper only under supervision.
References
- Clinical pharmacology of clonidine — antihypertensive & central alpha-2 agonist uses.
- Guidelines for resistant hypertension and withdrawal management.
- International ADHD and autonomic disorder recommendations (specialist indications).
Marketer details
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Lab tests offered by us
- Blood pressure monitoring
- Heart rate assessment
- Mental health screening if needed
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