Description

Axcer 90 mg (Ticagrelor) – Maintenance Dose Post‑Acute Coronary Syndrome

Axcer 90 mg Tablet contains ticagrelor, a P2Y₁₂ receptor antagonist indicated for preventing cardiovascular death, myocardial infarction, and stroke in adults with acute coronary syndrome or a history of MI—used in dual antiplatelet therapy (DAPT) with low-dose aspirin.

Key Benefits:

• Reduces risk of recurrent MI, stroke, and CV death in ACS patients 
• Clinically proven maintenance dose: 90 mg twice daily following a 180 mg loading dose 
• Rapid action and does not require metabolic activation—more consistent platelet inhibition than clopidogrel

How It Works

Ticagrelor reversibly inhibits the P2Y₁₂ platelet receptor, preventing activation and aggregation and thereby reducing the formation of harmful clots. 

Dosage & Administration

• Initial loading dose: 180 mg orally
• Maintenance: **90 mg twice daily**, starting approximately 6–12 hours after the loading dose
• Continue for up to **12 months post‑ACS**, then consider reducing to 60 mg twice daily, as clinically appropriate. Must be co-administered with aspirin 75–100 mg daily. 

Common Side Effects

• Bleeding (e.g. GI, intracranial), bruising, epistaxis—most serious risk 
• Shortness of breath (dyspnea)—generally mild, often improves over time 
• Dizziness, headache, nausea, hyperuricemia, elevated liver enzymes or hypotension may occur

Precautions & Interactions

• Avoid in active bleeding or history of intracranial hemorrhage. Not for severe hepatic impairment or hypersensitivity to ticagrelor or aspirin 
• Concurrent use of strong CYP3A4 inhibitors (e.g. ketoconazole) or inducers (e.g. rifampin, carbamazepine) may alter plasma levels—bleeding risk increases
• Avoid NSAIDs, concurrent anticoagulants, higher-than-recommended aspirin (>100 mg)—increased bleeding risk 
• Stopping abruptly may elevate risk of thrombotic events—do not discontinue without clinician guidance 

Why Choose Axcer?

• Sun Pharma’s ticagrelor tablet—generic equivalent of Brilinta with the same efficacy and twice-daily dosage 
• Proven cardiovascular benefits in high-risk patients per PLATO and other trials
• Cost-effective choice in India for standard dual antiplatelet therapy

Frequently Asked Questions (FAQs)

1. What is Axcer 90 mg prescribed for?

Used as maintenance dual antiplatelet therapy following ACS or MI to reduce risk of death, MI, or stroke. 

2. How soon does Axcer begin to work?

Effects begin within ~30 minutes; steady therapeutic levels reached soon after loading dose. 

3. What if I miss a dose?

Take it as soon as you remember, unless it’s near the next scheduled dose. Do not double up. 

4. Can I take Axcer with or without food?

Yes—can be taken with or without food, but consistency at the same time each day is recommended. 

5. Should I monitor labs?

Yes—periodic monitoring for bleeding, liver function, hemoglobin, and uric acid is advised per clinician discretion.