Cefix 100 mg (Cefixime)
Cefix 100 mg contains cefixime, a third-generation oral cephalosporin antibiotic used to treat a variety of bacterial infections. Cefixime works by interfering with bacterial cell wall synthesis, leading to bacterial death. It is commonly prescribed for respiratory tract infections, otitis media (middle ear infections), uncomplicated urinary tract infections (UTIs), pharyngitis/tonsillitis and some sexually transmitted infections. Cefixime is valued for its broad activity against many Gram-negative and some Gram-positive organisms and for convenient oral dosing.
Product introduction
Cefix 100 mg tablets are formulated for oral use and typically prescribed as either a once-daily or twice-daily regimen depending on indication and local guidelines. The 100 mg strength provides a flexible option for adults, adolescents and in some cases adjusted pediatric dosing (follow prescriber instructions). As a third-generation cephalosporin, cefixime combines broad Gram-negative coverage with reasonable tolerability and is often chosen where oral therapy is required.
Cefix is a prescription medicine — use only when prescribed by a licensed healthcare professional and according to the indicated dosing schedule.
Uses of Cefix 100 mg (Cefixime)
Common clinical indications for cefixime include:
- Acute otitis media (middle ear infection)
- Pharyngitis and tonsillitis when caused by susceptible bacteria
- Acute bacterial sinusitis
- Bronchitis and community-acquired pneumonia (selected outpatient cases)
- Uncomplicated urinary tract infections (UTIs) in adults
- Gonorrhea (single-dose regimens used historically; follow current local guidelines due to resistance concerns)
- Other infections caused by cefixime-sensitive organisms as guided by culture & sensitivity
Note: Antimicrobial choice should be guided by local resistance patterns and clinician judgement. For some infections, culture and sensitivity testing may be indicated to confirm cefixime susceptibility.
Benefits of Cefix 100 mg (Cefixime)
Benefits of using cefixime appropriately include:
- Broad coverage against many Gram-negative bacteria (e.g., Haemophilus influenzae, Escherichia coli)
- Convenient oral dosing — formulations available for once or twice daily administration
- Usually well tolerated with a predictable safety profile
- Useful outpatient option to avoid IV therapy in selected cases
In Treatment of Specific Infections
Cefixime is frequently used for otitis media in children, uncomplicated UTIs in adults, and selected respiratory infections. For sexually transmitted infections like gonorrhea, always follow the latest public health guidance due to evolving resistance.
Side effects of Cefix 100 mg (Cefixime)
Most side effects are mild and transient. If serious adverse events occur, seek medical advice immediately.
Common side effects
• Diarrhoea or loose stools
• Nausea and abdominal discomfort
• Flatulence
• Headache
Serious but uncommon: allergic reactions (including anaphylaxis), severe skin reactions, Clostridioides difficile-associated diarrhoea (which can be severe), hepatic abnormalities, and rare blood dyscrasias. If you experience rash, difficulty breathing, persistent high fever, bloody diarrhoea or yellowing of the skin/eyes, stop the medicine and seek urgent care.
How to use Cefix 100 mg (Cefixime)
Follow the prescriber’s instructions. Typical dosing examples (may vary by country & indication):
- Adults: commonly 100 mg once or twice daily depending on infection (follow prescriber).
- Children/adolescents: dose based on weight and local guidelines — use paediatric formulations if prescribed.
- Swallow tablets whole with water — may be taken with or without food; taking with food can reduce mild GI upset.
- Complete the full course even if you feel better before it finishes, unless your clinician instructs otherwise.
Never self-adjust dose or duration — misuse contributes to treatment failure and antibiotic resistance.
How Cefix 100 mg (Cefixime) works
Cefixime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). This action weakens the bacterial cell wall, resulting in cell lysis and death of susceptible bacteria. As a beta-lactam antibiotic, cefixime is bactericidal and most effective against actively dividing bacteria.
Safety advice
| Allergy | Do not take cefixime if you have a history of severe allergic reaction to cephalosporins or penicillins; discuss cross-reactivity risk with your prescriber. |
| Pregnancy | Use only if clearly needed and prescribed. Discuss risks and benefits with your clinician. |
| Breastfeeding | Cefixime is excreted in small amounts in breastmilk; consult your prescriber if breastfeeding. |
| Liver / Kidney disease | Dose adjustment may be required in significant renal impairment; inform your prescriber of existing conditions. |
| Drug interactions | Inform your prescriber about concurrent medicines; cefixime has relatively few major systemic interactions but always check with your clinician or pharmacist. |
What if you forget to take Cefix 100 mg?
If you miss a dose, take it as soon as you remember. If it is near the time for the next dose, skip the missed dose and continue. Do not double doses to make up for missed ones. If you have missed several doses, contact your prescriber for advice.
All substitutes
Substitutes depend on infection and local availability. Examples include:
- Other oral cephalosporins (e.g., cefuroxime, cefpodoxime) — prescriber choice based on susceptibility
- Penicillins (amoxicillin/clavulanic acid) where appropriate and not contraindicated
- Macrolides (azithromycin, clarithromycin) for selected respiratory infections (depending on susceptibility)
Selection of alternatives should be guided by culture results, allergy history, and local resistance patterns.
Quick tips
- Take the full prescribed course to prevent relapse and resistance.
- Report severe diarrhoea, rash, or allergic symptoms immediately.
- Store tablets in original packaging at room temperature.
- Inform your prescriber about penicillin allergy — cross-reactivity risk exists but is low.
Fact Box
| Generic name | Cefixime |
| Brand | Cefix 100 mg |
| Drug class | Third-generation oral cephalosporin |
| Form | Oral tablet |
| Typical dosing | 100 mg once or twice daily (prescriber determined) |
| Prescription | Prescription-only |
Patient concerns
Will cefixime treat my cold or flu? No. Cefixime treats bacterial infections, not viral illnesses like the common cold or influenza.
How soon will I feel better? Many patients notice symptom improvement within 48–72 hours; complete the full course as prescribed.
User feedback
Patients commonly report good tolerability and quick improvement in symptoms for indicated infections when cefixime is used appropriately. As with all antibiotics, adherence to the full course and follow-up if symptoms persist are important.
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FAQs
Can Cefix 100 mg be stopped when symptoms are gone?
No. Complete the prescribed course unless your prescriber advises otherwise. Stopping early increases relapse and resistance risk.
Can I take cefixime if I’m allergic to penicillin?
Tell your prescriber about any penicillin allergy. Cross-reactivity between penicillins and cephalosporins is possible but low; your prescriber will assess risk and choose a safe option.
Will cefixime cause diarrhoea?
Diarrhoea is a common side effect; if it is severe, bloody or persistent, seek medical attention (possible C. difficile infection).
How should I store and dispose of cefixime?
Store at room temperature away from moisture. Dispose of unused medicine via pharmacy take-back or local waste guidance.
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Share this article with friends or family who may benefit. Proper antibiotic use supports public health and reduces resistance.
Disclaimer:
This page is for educational purposes only and does not replace medical advice. Always follow your prescriber’s instructions and consult a healthcare professional for personalised recommendations.
References
- Standard antimicrobial prescribing guidelines and cephalosporin monographs
- National infectious disease treatment recommendations
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- Culture & sensitivity testing for respiratory and urine pathogens
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