Description

Cipro 750 mg (Ciprofloxacin): Powerful Oral Antibiotic for Serious Bacterial Infections

Cipro 750 mg tablets contain ciprofloxacin hydrochloride, a second-generation fluoroquinolone antibiotic used to treat a wide range of serious infections. It’s prescribed for complicated urinary tract infections, respiratory, gastrointestinal, bone/joint infections, typhoid fever, and other resistant Gram-negative pathogens. 

🎯 Indications & Usual Dosage

• Typical regimen: **750 mg orally every 12 hours**, often for 7–14 days (longer for bone/joint infections). 
• Used in complicated UTIs, pyelonephritis, bone and joint infections, typhoid, gastrointestinal infections including traveler’s diarrhea, and respiratory tract infections.

⚠️ Warnings & Serious Side Effects

• Increased risk of **tendonitis and tendon rupture**, particularly Achilles tendon—especially in patients over 60 or on corticosteroids—may occur during or months after treatment. 
• Central nervous system effects: seizures, peripheral neuropathy, hallucinations, mood changes—can appear even after the first dose. 
• Risk of QT prolongation leading to arrhythmia; monitor if combined with other QT‑prolonging medications. 
• May cause **Clostridioides difficile-associated diarrhea**, Stevens-Johnson syndrome, liver injury, photosensitivity, and exacerbation of myasthenia gravis. 

🩺 Common Side Effects

• Nausea, diarrhea, vomiting, headache, dizziness, rash. Usually mild and often resolve with time. 

📋 Administration Guidelines & Interactions

• Swallow tablets whole with water; may be taken with or without food. Avoid dairy, calcium, or antacids within ±2 hours to prevent absorption issues. 
• Ciprofloxacin inhibits CYP1A2; interacts with drugs like tizanidine (contraindicated), theophylline, clozapine, etc.—monitor closely. 
• Avoid in children (except limited indications like anthrax), pregnant or breastfeeding women due to potential cartilage or musculoskeletal toxicity. 

✅ Why Cipro 750 mg?

• High oral bioavailability (~70%) supports systemic treatment of serious Gram-negative infections. 
• Powerful broad-spectrum agent covering pathogens like Pseudomonas aeruginosa often resistant to other antibiotics. 
• Well-established dosage and safety profiles with clearly defined serious adverse event warnings. 

❓ Frequently Asked Questions (FAQs)

1. What if I miss a dose?

If less than 6 hours remain until next dose, skip the missed dose. Otherwise, take when remembered. Do not double dose. 

2. Can I take it with food?

Yes—food does not significantly affect absorption. Still avoid dairy or antacids around dosing times. 

3. How long is it safe to take?

Follow your provider’s instructions—typically 7–14 days; longer courses (e.g. 6–8 weeks) may be needed for bone/joint infections. 

4. When should I stop it?

Seek medical care if tendon pain, new neurological symptoms, allergic reactions, or severe diarrhea develop—these warrant immediate discontinuation. 

5. Can elderly or kidney-impaired patients use it?

Use with caution. Dose adjustments may be required in renal impairment; elderly patients have higher risk of tendon damage and CNS effects.