Description
Metolar XR 50 mg (Metoprolol Succinate ER) – Cardioselective Beta‑Blocker with Once‑Daily Convenience
Metolar XR 50 mg capsule contains metoprolol succinate extended-release (ER), a β₁‑selective blocker indicated for treating hypertension, chronic stable angina, post‑MI management, and heart failure in systolic dysfunction.
Key Uses:
- High blood pressure control
- Relief from angina and reduced chest pain episodes
- Improvement in symptoms and survival in systolic heart failure
- Secondary prevention post‑myocardial infarction
How It Works
Metoprolol selectively blocks β₁‑adrenergic receptors in the heart, leading to slower heart rate, reduced cardiac output, decreased oxygen demand, and lower blood pressure. Its lipophilicity also influences central nervous system effects.
Recommended Dosage
- Hypertension or Angina: start at 25–50 mg once daily; maintenance range 100–400 mg/day.
- Heart Failure: initiate at 12.5–25 mg daily (if severe); titrate gradually every 2 weeks to target 200 mg/day as tolerated.
Common Side Effects
- Dizziness, fatigue, headache, nausea, diarrhea, cold extremities, drowsiness, insomnia, vivid dreams
- Bradycardia, hypotension, potential sexual dysfunction or mood changes
- May mask diabetes symptoms—monitor blood sugar carefully.
Precautions & Interactions
- Abrupt cessation can trigger rebound tachycardia, hypertension, or angina—gradually taper under medical supervision.
- Contraindicated in severe bradycardia, AV block, uncompensated heart failure, cardiogenic shock, or asthma/COPD exacerbations.
- Use caution in diabetes, thyroid disorders, peripheral vascular disease, and renal/liver impairment.
- Drug interactions: CYP2D6 inhibitors, digoxin, calcium channel blockers, clonidine, NSAIDs may potentiate effects or side effects.
Why Choose Metolar XR?
- Once-daily extended-release formulation supports adherence and stable 24‑hour beta blockade
- Cardioselective profile minimizes bronchospasm risks seen in non-selective agents
- Available in India via Torrent—affordable and widely accessible ER metoprolol option
Frequently Asked Questions (FAQs)
1. What is Metolar XR 50 mg used for?
It treats hypertension, angina, heart failure, and is used to reduce mortality post‑MI with once-daily dosing.
2. How quickly does it work?
Starts lowering heart rate/blood pressure within hours; full therapeutic effects may take several weeks.
3. What if I miss a dose?
Take it when remembered if same day. If it’s near the next dose, skip; do not double up.
4. Can I take it with food?
Yes—can be taken with or without food. Do not crush or chew ER capsule.
5. Is lab monitoring necessary?
Monitor heart rate, blood pressure, and for side effects. In heart failure, kidney function and electrolytes should also be assessed.
