Description

Nitrogesic 0.2 % (30 g Nitroglycerin Ointment) – Sphincter-Relaxing Relief for Anal Pain

Nitrogesic 0.2 % ointment contains nitroglycerin (glyceryl trinitrate) 0.2 % w/w, a topical vasodilator licensed in India for relieving pain from anal fissures and hemorrhoids. By relaxing the sphincter muscles, it reduces pressure and promotes healing. 

How It Works

• Nitroglycerin donates **nitric oxide**, which dilates the internal anal sphincter and improves blood flow—reducing spasms and enabling fissure healing. 

Key Uses

• Relief of pain, burning, and discomfort from chronic anal fissures.
• Soothe inflammation and discomfort due to hemorrhoids or post-hemiffectomy pain—used off‐label.

Dosing & Application

Adults: Apply approx **1 inch (≈ 2.5 cm)** of ointment—equivalent to an initial nitroglycerin dose of ~1.5 mg—**twice daily** for up to **3 weeks**. Use the applicator guide or fingertip (with plastic glove) to apply around anus or just inside the anal canal. Do not exceed recommended duration due to tolerance risk. 

Common Side Effects

• Headache—very common (up to 20‑25 % incidence), usually diminishes after several applications. 
• Other effects: dizziness, lightheadedness, faintness, local irritation, nausea—typically mild and transient. 

Warnings & Precautions

• Avoid concurrent use of medications for erectile dysfunction (PDE‑5 inhibitors like sildenafil)—causes severe hypotension. 
• Do not ingest. For external/anorectal use only. Avoid eye or mucosal contact, wash hands thoroughly. 
• Not recommended in patients with severe anemia, glaucoma, low blood pressure, or increased intracranial pressure.
• Avoid use in pregnant or breastfeeding women unless advised by physician. 
• Up to 12 hours of daily topical exposure may lead to tolerance—clinicians often recommend a nitrate-free interval per day. 

Why Choose Nitrogesic?

• Available in a 30 g tube for convenient duration (≈ 1 inch dose × 6 weeks) 
• Formulation by Troikaa Pharmaceuticals, widely stocked and price-accessible in India 
• Focused strength (0.2 %) reduces headache risk while retaining efficacy in fissure pain relief. 

❓ Frequently Asked Questions (FAQs)

1. Can Nitrogesic heal anal fissures?

Clinical trials of higher‑strength GTN ointment (0.4 %) have shown 40‑50 % healing rates over 3 weeks. Nitrogesic 0.2 % may be less potent but still beneficial for symptom relief. 

2. What if I get headaches from it?

Headache is common, especially in the first days. Taking paracetamol or reducing dose often helps. Do not discontinue unless severe. 

3. Can I apply it inside the anus?

Yes—with a plastic-covered finger, insert a small amount up to the first finger joint and apply gently. If painful, apply externally around the anus.

4. May I use it longer than 3 weeks?

Long-term use increases risk of tolerance and systemic nitrate effects. Do not extend beyond recommended period without medical advice.

5. Is Nitrogesic safe with heart conditions?

Avoid using with other nitrates or medications like sildenafil due to blood pressure drop risk. Use with caution in heart disease—consult your healthcare provider.