Description

Nitrosmart 2.6 mg (Nitroglycerin Controlled‑Release Tablet)

Nitrosmart 2.6 mg contains 2.6 mg of nitroglycerin (glyceryl trinitrate) in a controlled‑release formulation by Healing Pharma, India. It is indicated for prevention and treatment of angina pectoris associated with coronary artery disease (CAD).

🔹 Mechanism of Action

Nitroglycerin is a vasodilator that releases nitric oxide in vascular smooth muscle, leading to venous dilation and reduced cardiac preload, thus lowering myocardial oxygen demand and relieving chest pain. 

🎯 Uses & Indications

• Prevention of exertional or stress-induced angina episodes
• Relief of acute angina attacks
• Supportive treatment in heart failure to reduce cardiac workload
• Off-label use for hypertensive emergencies and anal fissure (topical form) 

Pill dosage is designed to avoid inpatient sublingual misuse and to extend symptom relief during daily activities. 

⚙️ Dosage & Administration

• Default dose: 2.6 mg controlled‑release tablet taken **every 6–8 hours**; typical range 2.5–6.5 mg Q6–8h based on tolerability.
• Swallow whole with water; do not chew or crush. May be taken with or without food. 

Tolerance can develop with CNS exposure, so clinicians avoid around-the-clock use and ensure nitrate-free intervals. 

📋 Side Effects

• Headache (most common), facial flushing, lightheadedness, dizziness, hypotension
• Reflex tachycardia, nausea or dizziness when standing up (orthostatic hypotension)
• Rare: syncope, methemoglobinemia, or rebound tachycardia upon abrupt discontinuation. 

⚠️ Precautions & Interactions

• Contraindicated with phosphodiesterase-5 inhibitors (e.g. sildenafil, tadalafil)—risk of severe hypotension. 
• Use with caution in hypovolemia, severe anemia, closed‑angle glaucoma, or increased intracranial pressure. 
• Avoid sudden withdrawal—withdrawal may precipitate severe angina or hypertension. Taper under supervision.
• Avoid in patients with CYP3A4 inducers/inhibitors for extended-release preparations. 

✅ Why Choose Nitrosmart 2.6 mg?

• Affordable Indian brand by Healing Pharma, widely stocked in pharmacies. 
• Low-dose controlled-release helps mitigate the risk of headache and tolerance.
• Approved for self-administration under prescription; simplifies outpatient angina management.

❓ Frequently Asked Questions (FAQs)

1. Can I chew or crush the tablet?

No—crushing or chewing disrupts controlled-release formulation, increasing side effects risk. Swallow whole with water. 

2. What if I feel dizzy or have a headache?

Dizziness or mild headache is common. Taking it with food or at bedtime often helps. Do not drive or operate machinery until your body adjusts. 

3. How often can I take this medication?

The usual dosing schedule is every 6 to 8 hours. Do not exceed the daily maximum of three to four doses unless advised by your physician. Tolerance risk increases with continuous use. 

4. Is it safe to take alcohol with Nitrosmart?

No—alcohol enhances hypotensive effects and increases risk of dizziness or fainting. It’s best avoided while taking this medicine.

5. Can women who are pregnant or breastfeeding use this?

Use only if clearly needed—nitroglycerin crosses the placenta and is excreted in breast milk. Consult your doctor before use.