Metformin 250 mg (Generic)
50.00$ – 95.00$Price range: 50.00$ through 95.00$
Product Overview Metformin 250 mg is a generic oral antihyperglycemic agent manufactured by USV Pvt Ltd. It is formulated for the management of type 2 diabetes mellitus. Each strip contains 10 tablets, each delivering 250 mg of metformin. The product
| Active Ingredients | Metformin |
|---|---|
| Delivery Time | 6 To 15 days |
| Indication | Type 2 diabetes |
| Manufacturer | USV Pvt Ltd |
| Packaging | 10 tablets in 1 strip |
| Strength | 250mg |
- Delivery & Return
Delivery
- If your order is damaged, delayed, or partially received, we will dispatch a new package or issue a full refund. For partial orders, you will only be charged for the items received, with the remaining balance refunded.
- Average shipping time via EMS is 1-4 weeks. Delivery may take up to 30 days due to postal disruptions from weather or natural disasters.
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- For any questions or queries regarding your order, contact us at support@genariccurerx.com.
Return & Refund
- We will reship or refund any lost orders if contacted within 8 weeks of the ship date. No reshipments or refunds after 8 weeks.
- We will replace undelivered orders if:
- An additional 7 days have passed since the standard delivery time.
- The shipping address provided is correct.
- For incorrect addresses, you will be charged for the replacement. If the original order is returned, we will process a refund, which may take time due to unpaid return postage.
Help
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- Phone: +91 9157057042
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Product Overview
Metformin 250 mg is a generic oral antihyperglycemic agent manufactured by USV Pvt Ltd. It is formulated for the management of type 2 diabetes mellitus. Each strip contains 10 tablets, each delivering 250 mg of metformin. The product is available in pack sizes of 100, 200, and 300 tablets, providing flexible options for long‑term therapy. Delivery typically occurs within 6 to 15 days, ensuring timely access to this essential medication.
What is Metformin 250 mg?
Metformin belongs to the biguanide class of glucose‑lowering drugs. It works by decreasing hepatic glucose production, improving peripheral insulin sensitivity, and enhancing peripheral glucose uptake. The 250 mg strength is a lower dose often used in combination therapy or for patients who require titration. This formulation is bioequivalent to the reference listed drug, offering the same clinical efficacy with a well‑established safety profile.
Uses and Benefits
The primary indication for Metformin 250 mg is the treatment of type 2 diabetes when lifestyle modification alone is insufficient. Clinical studies demonstrate that Metformin improves glycemic control, reduces HbA1c by approximately 1.5 to 2 percent, and does not cause weight gain. Additional benefits include modest improvements in cardiovascular risk markers and a low propensity for hypoglycemia when used alone. Patients often appreciate the convenience of a once‑or‑twice‑daily dosing schedule and the availability of multiple pack sizes to suit individual needs.
How It Works
Metformin exerts its antihyperglycemic effect through several mechanisms. First, it inhibits gluconeogenesis in the liver, reducing the liver’s output of glucose. Second, it enhances peripheral insulin sensitivity, allowing muscle cells to take up glucose more efficiently. Third, it modestly decreases intestinal absorption of glucose. These actions collectively lower fasting and post‑prandial blood glucose levels without stimulating insulin secretion, which explains its low risk of causing hypoglycemia. The medication is absorbed rapidly from the gastrointestinal tract, reaches peak plasma concentrations within two to three hours, and is excreted unchanged by the kidneys.
Dosage Guidelines
Typical initiation involves one tablet of Metformin 250 mg taken with the morning meal. The dose may be titrated upward based on glycemic response, usually to a maximum of 2000 mg per day divided into two doses. Patients should follow the titration schedule provided by their healthcare provider and should not exceed the recommended daily dose. The tablets should be swallowed whole with water and may be taken with food to reduce gastrointestinal discomfort. Adjustments are necessary in patients with impaired renal function, asMetformin is cleared renally.
Side Effects
Most patients tolerate Metformin well, but some may experience gastrointestinal symptoms such as nausea, diarrhea, abdominal discomfort, or a metallic taste. These effects are usually mild and transient, often improving with dose titration or taking the tablet with meals. Rare but serious adverse events include lactic acidosis, particularly in individuals with severe renal impairment, hepatic disease, or conditions predisposing to hypoxia. Patients should be advised to seek immediate medical attention if they experience persistent vomiting, abdominal pain, muscle weakness, or unexplained fatigue, which may signal lactic acidosis.
Warnings and Precautions
Before initiating Metformin 250 mg, clinicians should assess renal function, hepatic status, and cardiac health. The medication is contraindicated in patients with an estimated glomerular filtration rate (eGFR) below 30 mL/min/1.73 m². Caution is also advised in those with a history of heart failure, recent myocardial infarction, or severe dehydration. Patients should avoid excessive alcohol consumption, as it may increase the risk of lactic acidosis. Pregnant or breastfeeding women should consult a healthcare professional before use, as the safety profile during these conditions requires careful evaluation. Regular monitoring of renal function is recommended during long‑term therapy.
Frequently Asked Questions
- Can Metformin 250 mg be taken with other diabetes medications? Yes, it is frequently combined with sulfonylureas, DPP‑4 inhibitors, or insulin. However, dosage adjustments may be necessary to prevent hypoglycemia.
- How long does it take to see a reduction in blood sugar levels? Most patients notice a modest decrease in fasting glucose within the first week, with maximal glycemic effect achieved after 2 to 3 weeks of consistent use.
- Is the 250 mg strength suitable for elderly patients? Lower doses such as 250 mg are often recommended for older adults to reduce the risk of gastrointestinal side effects and to accommodate potential declines in renal function.
- Where can I find more detailed prescribing information? The official FDA label and the product monograph available on the USV website provide comprehensive dosing, contraindications, and safety data.
- Does Metformin cause weight loss? Metformin is weight‑neutral; it typically does not cause significant weight loss, though it may help prevent weight gain associated with other glucose‑lowering agents.
For additional scientific insight, refer to resources such as the National Institutes of Health, the U.S. Food and Drug Administration, and MedlinePlus. More detailed drug information is available on Drugs.com and the Wikipedia entry on Metformin.
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