Glibenclamide 5 Mg (Generic)

Price range: 45.00$ through 70.00$

Product Overview Glibenclamide 5 Mg is a widely prescribed oral antidiabetic medication used in the management of Type 2 diabetes mellitus. Manufactured by Aristo Pharmaceuticals Pvt. Ltd. , this generic formulation delivers a consistent 5 mg dose o

Active Ingredients	Glibenclamide
Delivery Time	6 To 15 days
Indication	Type 2 diabetes
Manufacturer	Aristo Pharmaceuticals Pvt. Ltd.
Packaging	10 tablets in 1 strip
Strength	5mg

Estimated Delivery: Sun, Aug 16 – Tue, Aug 18

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Pack Size	Price	Quantity
120 Tablet/s	45.00$
180 Tablet/s	58.00$
300 Tablet/s	70.00$

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United States

Standard tracked delivery

7–14 Business Days

United Kingdom

Standard tracked delivery

5–10 Business Days

Australia

Standard tracked delivery

10–18 Business Days

Rest of World

50+ countries available

10–20 Business Days

All orders are shipped in plain, discreet packaging with no pharmacy or medicine reference outside. Tracking number is sent by email after dispatch. Shipped from Mumbai, India.

Description

Product Overview

Glibenclamide 5 Mg is a widely prescribed oral antidiabetic medication used in the management of Type 2 diabetes mellitus. Manufactured by Aristo Pharmaceuticals Pvt. Ltd., this generic formulation delivers a consistent 5 mg dose of glibenclamide in a convenient strip of 10 tablets. The product is available in pack sizes of 120, 180, and 300 tablets, offering flexibility for patients and clinicians seeking reliable blood‑glucose control. Shipping typically takes 6 to 15 days, ensuring a timely supply for ongoing therapy.

What is Glibenclamide

Glibenclamide, also known as glyburide in some regions, belongs to the sulfonylurea class of drugs. It functions primarily by stimulating the pancreatic beta‑cells to release insulin, thereby lowering fasting and post‑prandial glucose levels. The active ingredient is Glibenclamide, and the medication is indicated for adults with Type 2 diabetes when diet and exercise alone are insufficient. For detailed scientific background, refer to the National Center for Biotechnology Information.

Uses and Benefits

The primary use of Glibenclamide 5 Mg is to improve glycemic control in patients with Type 2 diabetes. Clinical studies have demonstrated that regular use can reduce HbA1c by approximately 0.5 to 1.0 % when combined with lifestyle modifications. Benefits include:

Effective reduction of fasting plasma glucose.
Convenient once‑daily dosing that supports adherence.
Cost‑effective generic alternative to brand‑name sulfonylureas.
Available in multiple pack sizes to suit individual treatment plans.

For additional information on diabetes management, consult the MedlinePlus database.

How It Works

Glibenclamide acts by binding to the sulfonylurea receptor (SUR1) on the surface of pancreatic beta‑cells. This interaction closes ATP‑sensitive potassium channels, leading to membrane depolarization and subsequent calcium influx, which triggers insulin secretion. The released insulin enhances peripheral glucose uptake and suppresses hepatic glucose production. The mechanism is well documented in peer‑reviewed literature, including reviews indexed by PubMed.

Dosage Guidelines

Dosage of Glibenclamide must be individualized by a qualified healthcare professional. Typical initiation is a low dose, often 2.5 mg once daily, which may be titrated based on glycemic response and tolerability. The drug is intended for oral administration and should be taken with breakfast or the first main meal of the day to minimize gastrointestinal discomfort. Patients should never adjust their dose without medical supervision. For comprehensive prescribing information, see the FDA drug database.

Side Effects

Like all medications, Glibenclamide can cause adverse effects. Most are mild and transient, but some may require medical attention. Common side effects include:

Hypoglycemia (low blood sugar) – the most serious risk.
Nausea, vomiting, or abdominal discomfort.
Headache or dizziness.
Skin rash or itching.

Rare but severe reactions such as hepatic dysfunction or severe hypersensitivity have been reported. If any sign of hypoglycemia occurs (e.g., sweating, tremors, confusion), immediate carbohydrate intake and medical evaluation are recommended. For a complete safety profile, refer to the Drugs.com monograph.

Warnings and Precautions

Before initiating therapy, healthcare providers should assess:

Renal or hepatic impairment, which may necessitate dose adjustment.
History of hypoglycemia or cardiac events.
Concurrent use of other antidiabetic agents that increase hypoglycemia risk.

Glibenclamide is contraindicated in patients with Type 1 diabetes, diabetic ketoacidosis, or severe renal disease. Pregnant or breastfeeding women should only use the medication under strict medical supervision. Store the tablets in a dry place, away from direct sunlight, and keep out of reach of children. For official prescribing information, consult the National Institutes of Health resources.

Frequently Asked Questions

Can Glibenclamide be used alongside insulin therapy? Yes, but only under close medical supervision, as the combination increases hypoglycemia risk.
How long does it take to see a reduction in blood glucose levels? Most patients notice a modest decline within 1–2 weeks, with maximal effect observed after several weeks of consistent use.
Is the medication safe for elderly patients? Caution is advised; lower initial doses are recommended due to increased sensitivity and potential for renal function decline.
What should I do if I miss a dose? Take the missed dose as soon as remembered unless it is near the time of the next scheduled dose; do not double up.
Are there dietary restrictions while taking Glibenclamide? No specific diet is required, but maintaining regular meals and monitoring carbohydrate intake helps prevent glucose fluctuations.