Susten 200 mg Injection (Progesterone)

Product Overview

Susten 200 mg injection is a pharmaceutical preparation of progesterone manufactured by Sun Pharmaceutical Industries Ltd. It is supplied in either a 1 ml ampule or a 2 ml vial, each containing 200 mg of progesterone per milliliter. The product is intended for intramuscular or subcutaneous administration under medical supervision. Pack sizes include 5, 10, or 15 ampoules/vials, providing flexibility for patients and clinicians. This medication falls under the category of female infertility treatments and hormone replacement therapy, offering a reliable option for ovulation induction and luteal phase support.

What is Susten 200 mg Injection

Susten contains progesterone, a synthetic analogue of the natural hormone that regulates the menstrual cycle and prepares the uterine lining for implantation. Progesterone is essential for maintaining early pregnancy and supporting the secretory phase of the endometrium. The injectable form delivers a consistent dose of 200 mg per milliliter, ensuring steady plasma levels. It is classified as a prescription‑only medication and must be prescribed by a qualified healthcare professional after appropriate evaluation.

Uses and Benefits

The primary indication for Susten 200 mg injection is the treatment of female infertility associated with luteal phase deficiency. It is also used as part of hormone replacement therapy for women experiencing menopausal symptoms related to estrogen deficiency. Clinical studies show that supplemental progesterone can improve endometrial receptivity, increase implantation rates, and reduce the risk of early miscarriage. Additionally, progesterone therapy may help regulate irregular menstrual cycles and support patients undergoing assisted reproductive technologies such as IVF.

How It Works

Progesterone exerts its effects by binding to intracellular progesterone receptors, which then translocate to the nucleus and modulate gene expression. This action promotes the transformation of the endometrium from a proliferative to a secretory state, making it more receptive to embryo implantation. In fertility protocols, progesterone supplementation is typically introduced after ovulation to mimic the natural luteal phase. The injectable route bypasses first‑pass metabolism, delivering the hormone directly into the bloodstream for rapid onset and predictable absorption.

Dosage Guidelines

Dosage of Susten 200 mg injection is individualized based on the patient’s diagnosis, age, and treatment protocol. For ovulation induction, a common regimen involves 200 mg administered intramuscularly every 24 hours for up to six days following a trigger ovulation agent. In hormone replacement cycles, 200 mg may be given subcutaneously every 2–3 days for several weeks. Patients should always follow the prescribing physician’s instructions and never adjust the dose without medical advice. The medication should be stored at 2–8 °C and protected from light until use.

Side Effects

Like all medications, Susten 200 mg injection can cause adverse reactions. Common side effects include mild pain or irritation at the injection site, headache, abdominal cramping, and transient breast tenderness. Less frequent but more serious events may involve allergic reactions, mood changes, or signs of thromboembolism such as swelling or shortness of breath. If any unexpected symptoms occur, patients should contact their healthcare provider promptly. For detailed safety information, refer to the drug’s prescribing information or reputable sources such as the U.S. Food and Drug Administration.

Warnings and Precautions

Susten is contraindicated in patients with known hypersensitivity to progesterone or any component of the formulation. It should not be used in individuals with active liver disease, unexplained vaginal bleeding, or a history of thromboembolic disorders. Caution is advised for patients with a history of breast cancer, ovarian cysts, or severe depression. Pregnant women should only use this medication under the supervision of a physician, as inappropriate use may affect fetal development. Always review the patient’s full medical history and current medications before initiating therapy.

Frequently Asked Questions

1. What condition does Susten 200 mg injection treat? It is primarily used to treat luteal phase deficiency and to support hormone replacement therapy in women with infertility or menopausal symptoms.

2. How is Susten administered? The medication is given by intramuscular or subcutaneous injection, typically in a clinical setting or under physician guidance at home.

3. Can Susten be used during pregnancy? It may be prescribed during early pregnancy only under medical supervision; self‑administration without oversight is not recommended.

4. Are there any drug interactions? Patients should inform their doctor about other hormonal therapies, anticoagulants, or medications that affect liver enzymes, as these may alter progesterone levels.

5. Where can I find more information? Detailed prescribing information is available from the manufacturer and can be accessed through trusted resources such as the MedlinePlus database or the National Institutes of Health.

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