Clomifene 50 mg (Clomiphene)

Price range: 50.00$ through 98.00$

Product Overview Clomifene 50 mg is a pharmaceutical tablet formulated to support ovulation in women experiencing infertility. Manufactured by Healing Pharma in India, each strip contains 10 tablets of 50 mg Clomiphene citrate. The product is availab

Pack Size	Price	Quantity
100 Tablet/s	50.00$
200 Tablet/s	75.00$
300 Tablet/s	98.00$

Estimated Delivery: Mon, Jun 22 – Wed, Jun 24

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Description

Product Overview

Clomifene 50 mg is a pharmaceutical tablet formulated to support ovulation in women experiencing infertility. Manufactured by Healing Pharma in India, each strip contains 10 tablets of 50 mg Clomiphene citrate. The product is available in pack sizes of 100, 200, or 300 tablets, offering flexibility for long‑term treatment plans. Packaging consists of a sealed strip designed to protect potency and maintain hygiene. This medication is indicated specifically for female infertility associated with anovulation or oligo‑ovulation, and is supplied with a standard delivery window of 6 to 15 days.

What Is Clomifene

Clomifene belongs to the class of selective estrogen receptor modulators (SERMs). It functions by blocking estrogen receptors in the hypothalamus, which leads to an increase in follicle‑stimulating hormone (FSH) and luteinizing hormone (LH) secretion. Elevated gonadotropins stimulate the ovary to develop and release a mature oocyte, thereby improving the chances of conception. The drug is chemically identified as clomiphene citrate and is widely referenced in authoritative sources such as the PubMed and the FDA database.

Uses and Benefits

The primary use of Clomifene 50 mg is the induction of ovulation in women who do not ovulate regularly. Clinically, it is employed for conditions such as polycystic ovary syndrome (PCOS) and unexplained infertility. Benefits include a non‑invasive oral administration route, a well‑characterized safety profile when used under medical supervision, and a cost‑effective alternative to more advanced assisted reproductive technologies. Evidence from systematic reviews indexed in MedlinePlus supports its efficacy in achieving ovulation in approximately 70 % of appropriately selected patients.

How It Works

Clomifene exerts its pharmacodynamic effect by acting as an antagonist at estrogen receptors in the central nervous system. This blockade reduces negative feedback on the hypothalamic‑pituitary axis, prompting an increase in gonadotropin‑releasing hormone (GnRH) pulses. Consequently, the anterior pituitary releases higher amounts of FSH and LH, which stimulate follicular development. The resulting follicular maturation culminates in ovulation, typically occurring 6 to 12 days after the final dose. Detailed mechanistic explanations can be found on the Wikipedia entry for Clomiphene.

Dosage Guidelines

Clomifene therapy is typically initiated under the supervision of a qualified healthcare professional. A common regimen involves a single daily dose of 50 mg for five consecutive days, usually beginning on the third to fifth day of the menstrual cycle. Subsequent cycles may be repeated after a monitoring period, with dosage adjustments made based on ovarian response and clinical judgment. Patients should never self‑administer without a prescription, and dosing should be individualized according to factors such as age, ovarian reserve, and prior response. For comprehensive guidance, refer to clinical practice guidelines available through the NIH.

Side Effects

Like all medications, Clomifene may cause adverse effects. The most frequently reported symptoms include hot flashes, abdominal discomfort, breast tenderness, and mild visual disturbances. Less common but clinically important reactions can involve ovarian hyperstimulation syndrome (OHSS), pelvic pain, and mood changes. Rarely, thromboembolic events have been documented. Patients are advised to report any persistent or severe symptoms to their physician promptly. The FDA provides a detailed safety summary for reference.

Warnings and Precautions

Clomifene is contraindicated in individuals with known hypersensitivity to the drug, liver disease, or those who are pregnant or breastfeeding. Prior to initiation, a thorough evaluation of ovarian function and uterine anatomy is recommended. Concomitant use with certain hormonal therapies may alter efficacy and should be discussed with a healthcare provider. Patients should be advised to avoid excessive alcohol consumption and to maintain a healthy body weight, as these factors can influence treatment outcomes. Ongoing monitoring through ultrasound or hormone assays is standard practice to mitigate the risk of complications.

Frequently Asked Questions

Is Clomifene safe for long‑term use? Clinical studies indicate that short‑term courses (up to six cycles) are well‑tolerated, but prolonged continuous use is not recommended without medical oversight.
Can Clomifene increase the chance of multiple pregnancies? Yes, the medication can stimulate the development of more than one follicle, leading to a modest increase in twins or higher‑order multiples.
How quickly does ovulation occur after the last dose? Ovulation typically happens within 6 to 12 days after the final tablet, though individual variation exists.
Do I need a prescription to purchase Clomifene? Yes, Clomifene is a prescription‑only medication and should be obtained under the guidance of a licensed clinician.
What should I do if I miss a dose? If a dose is missed, the patient should contact their healthcare provider for instructions; restarting the cycle without professional guidance is not advised.