Avanafil 50 mg

Price range: 74.00$ through 124.00$

Product Overview Avanafil 50 mg is a prescription medication formulated to address erectile dysfunction in adult men. It is manufactured by Sunrise Remedies Pvt Ltd and supplied in a strip containing four tablets. The product is marketed in pack size

Pack Size	Price	Quantity
40 Tablet/s	74.00$
60 Tablet/s	100.00$
80 Tablet/s	124.00$

Estimated Delivery: Mon, Jun 15 – Wed, Jun 17

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All orders are shipped in plain, discreet packaging with no pharmacy or medicine reference outside. Tracking number is sent by email after dispatch. Shipped from Mumbai, India.

Description

Product Overview

Avanafil 50 mg is a prescription medication formulated to address erectile dysfunction in adult men. It is manufactured by Sunrise Remedies Pvt Ltd and supplied in a strip containing four tablets. The product is marketed in pack sizes of 40, 60, and 80 tablets, offering flexibility for patients who require ongoing therapy. Each tablet delivers a 50 mg dose of the active ingredient avanafil, a phosphodiesterase type 5 (PDE5) inhibitor that has received regulatory approval for the treatment of impotence. The packaging emphasizes discreet delivery and clear dosing instructions, supporting safe use under medical supervision.

What is Avanafil 50 mg

Avanafil belongs to a class of drugs known as PDE5 inhibitors. It works by enhancing the natural physiological response to sexual stimulation. The compound is chemically described as 3-(2‑fluoro‑4‑pyridyl)-5‑[2‑(1‑methyl‑pyrrolidin‑3‑yl)‑ethyl]-1H‑indole. While the full chemical name is rarely used in clinical practice, the therapeutic effect is well documented. Avanafil is distinct from other agents such as sildenafil or tadalafil in its rapid onset of action, with many users reporting effectiveness within 15 minutes of ingestion. The medication is intended for oral administration and should be taken whole, without crushing or chewing.

Uses and Benefits

The primary indication for avanafil 50 mg is the improvement of erectile function in men who experience difficulty achieving or maintaining an erection sufficient for satisfactory sexual activity. Clinical studies have demonstrated that the drug can significantly increase the International Index of Erectile Function (IIEF) scores compared with placebo. Benefits include a faster onset of effect, allowing for more spontaneous intimacy, and a lower incidence of visual disturbances relative to some alternative therapies. Additionally, the medication is available in several pack sizes, enabling patients to select a quantity that matches their treatment plan while maintaining cost efficiency.

How It Works

During sexual stimulation, the nervous system releases nitric oxide in the penile tissue, which activates the enzyme guanylate cyclase. This leads to an increase in cyclic guanosine monophosphate (cGMP), causing smooth muscle relaxation and increased blood flow to the penis. The enzyme phosphodiesterase type 5 normally breaks down cGMP, but avanafil blocks this action, prolonging the vasodilatory effect. The result is a sustained erection when sexual arousal is present. Because the drug requires sexual stimulation to work, it does not produce an erection in the absence of arousal, preserving the natural physiological context.

Dosage Guidelines

The recommended starting dose of avanafil is one 50 mg tablet taken approximately 30 minutes before anticipated sexual activity. The tablet should be swallowed with a full glass of water. Patients may adjust the dose to 100 mg based on efficacy and tolerability, but should not exceed one tablet per day. Administration with a high‑fat meal may delay absorption, so it is advisable to take the medication on an empty stomach or with a light meal. For individuals over the age of 65 or those with hepatic impairment, a lower dose may be appropriate, and consultation with a healthcare professional is recommended before any dose modification.

Administration Tips

Patients should store the tablets at room temperature, away from moisture and direct sunlight. It is important to keep the medication out of reach of children and pets. If a dose is missed, the tablet should not be taken later in the day; the next scheduled dose should be skipped, and the regular dosing schedule resumed. Consistency in timing helps maintain steady drug levels and reduces the likelihood of missed doses.

Side Effects

Like all pharmaceutical products, avanafil can produce adverse reactions. The most frequently reported side effects include headache, facial flushing, nasal congestion, and mild dizziness. These symptoms are typically transient and resolve without medical intervention. Less common effects may involve back pain, muscle aches, or a temporary decrease in blood pressure. Although rare, serious complications such as priapism (prolonged erection lasting more than four hours), sudden vision loss, or abrupt hearing impairment require immediate medical attention. Patients should be instructed to seek emergency care if they experience any of these severe outcomes.

Monitoring and Follow‑up

Regular follow‑up appointments with a healthcare provider are recommended to assess the effectiveness of therapy and to monitor for any emerging side effects. Blood pressure and cardiovascular status should be evaluated periodically, especially in patients with pre‑existing heart conditions. Laboratory tests are generally not required, but physicians may request a basic metabolic panel if there are concerns about liver function. Patients should report any new symptoms promptly, as early intervention can prevent complications.

Warnings and Precautions

Avanafil is contraindicated in patients who are using nitrate‑containing medications for chest pain or heart conditions, as the combination can cause a sudden, dangerous drop in blood pressure. It is also not indicated for use in women or children under the age of 18. Individuals with a history of cardiovascular disease, including recent heart attack, angina, or irregular heart rhythm, should discuss their medical history with a physician before initiating therapy. Alcohol consumption should be limited, as it may increase the risk of dizziness or hypotension. Proper storage in a dry place away from direct heat is essential to maintain potency. For detailed prescribing information, see the FDA prescribing information.

Drug Interactions

Avanafil can interact with several classes of medications, including alpha‑blockers, antihypertensives, and certain antifungal agents. Co‑administration with strong CYP3A4 inhibitors may increase plasma concentrations of the drug, necessitating a dose adjustment. Conversely, CYP3A4 inducers may reduce its efficacy. Patients taking medications for pulmonary hypertension or other erectile dysfunction treatments should disclose all current prescriptions to their prescribing clinician to avoid adverse interactions.

Frequently Asked Questions

Q1: How quickly does avanafil work? A: Most users notice an improvement in erectile function within 15 to 30 minutes after taking the tablet, making it one of the faster‑acting options for erectile dysfunction.

Q2: Can avanafil be taken with food? A: It can be taken with or without food, but a large high‑fat meal may delay absorption, so a light meal is preferred for consistent results.

Q3: Is it safe to combine avanafil with other erectile dysfunction medications? A: No, combining avanafil with other PDE5 inhibitors or similar therapies is not recommended, as it may increase the risk of side effects.

Q4: How long does the effect of a single dose last? A: The therapeutic effect typically persists for up to six hours, allowing for multiple attempts at intercourse within that window.

Q5: Where can I find more detailed prescribing information? A: Detailed prescribing information is available on the FDA label for avanafil and through reputable medical resources such as MedlinePlus and the NIH clinical guidelines.