Persol AC 5% Gel (Benzoyl Peroxide)

Product Overview

Persol AC 5% Gel is a topical acne medication manufactured by Wallace Pharmaceuticals Pvt. Ltd. The product is supplied in a 30 gm tube and contains 5% benzoyl peroxide as the active ingredient. It is indicated for the treatment of mild to moderate facial acne vulgaris. The gel formulation provides a convenient way to apply the medication evenly over affected skin areas. This medication is available in various pack sizes, including 1 tube, 3 tubes, and 6 tubes, allowing patients to choose a quantity that fits their treatment plan. Shipping typically takes between 6 to 15 days depending on the destination. For more detailed prescribing information, refer to the FDA label FDA

What is Persol AC 5% Gel

Persol AC 5% Gel belongs to the class of topical anti‑infective agents used in dermatology. The active component, benzoyl peroxide, works by releasing oxygen in the skin, creating an environment that is hostile to anaerobic bacteria such as Propionibacterium acnes. This mechanism helps reduce the bacterial load and inflammation associated with acne lesions. The gel is classified as an over‑the‑counter (OTC) acne treatment in many markets, though it is also produced under prescription strength in some regions. Its non‑comedogenic base makes it suitable for use on oily and acne‑prone skin without worsening pore blockage.

Uses and Benefits

The primary use of Persol AC 5% Gel is to reduce the number and severity of acne papules and pustules. Clinical studies have demonstrated that regular application can lead to visible improvement in skin clarity within two to four weeks of consistent use. In addition to its antibacterial action, the gel helps to dry out excess oil and can aid in the removal of dead skin cells, further decreasing the likelihood of clogged pores. Patients often report a reduction in redness and swelling, which contributes to a smoother complexion. The 5% strength is considered potent enough for most mild to moderate acne while generally avoiding the need for systemic antibiotics. This makes it a valuable option for individuals seeking a non‑prescription solution that can be integrated into a broader skin‑care routine.

How It Works

When applied to the skin, benzoyl peroxide undergoes enzymatic breakdown that releases reactive oxygen species. These species oxidize cellular components of acne‑causing bacteria, leading to bacterial death. Simultaneously, the oxidative environment helps to unclog pores by breaking down sebum and keratin plugs. The gel’s penetration is relatively shallow, which limits systemic exposure while still delivering an effective local concentration. This dual action — antibacterial and keratolytic — makes benzoyl peroxide a cornerstone in acne therapy. For a comprehensive overview of the chemistry behind benzoyl peroxide, see the National Center for Biotechnology Information (NCBI) resource NCBI Bookshelf

Dosage Guidelines

To achieve optimal results, apply a thin layer of Persol AC 5% Gel to the cleaned, dried affected areas once daily, preferably in the evening. Start with a small amount — about the size of a pea — to assess skin tolerance, then gradually increase to the full recommended dose if no irritation occurs. The gel should not be used on broken skin, mucous membranes, or near the eyes. Avoid excessive washing of the treated area, as this can exacerbate dryness. If a dose is missed, apply it as soon as remembered unless it is close to the time of the next application; in that case, skip the missed dose and resume the regular schedule. Patients should avoid using other harsh skin products, such as strong exfoliants or alcohol‑based toners, on the same areas to reduce the risk of irritation. For additional guidance on acne treatment protocols, consult the MedlinePlus page on acne MedlinePlus

Side Effects

Most users experience mild and transient side effects, which typically diminish with continued use. Common reactions include skin dryness, peeling, and mild erythema at the site of application. Some individuals may notice a temporary burning or stinging sensation shortly after application; this usually resolves within a few minutes. Less frequently, excessive dryness or contact dermatitis can occur, particularly in patients with sensitive skin. If severe irritation, swelling, or signs of an allergic reaction develop, discontinue use and seek medical advice. It is important to keep the medication out of reach of children and to store it at room temperature away from direct sunlight. For a detailed list of reported adverse events, refer to the Drugs.com database Drugs.com

Warnings and Precautions

Before using Persol AC 5% Gel, patients should consider the following precautions: avoid contact with the eyes, lips, and nostrils; if accidental contact occurs, rinse thoroughly with water. Individuals with known hypersensitivity to benzoyl peroxide or any of the excipients should not use this product. The gel is flammable; keep it away from open flames or high heat sources. Pregnant or breastfeeding women should consult a healthcare professional before initiating treatment, as the safety data in these populations is limited. Do not apply to large surface areas without medical supervision. Keep the tube tightly closed when not in use to prevent oxidation of the gel. Store at temperatures below 30 °C (86 °F) and discard any product that changes color or consistency. For official regulatory information, visit the Wallace Pharmaceuticals website or contact the manufacturer directly.

Frequently Asked Questions

Can Persol AC 5% Gel be used on the back or chest?

Yes, the gel can be applied to any area affected by acne, including the back and chest, provided the skin is clean and dry before application.

How long does it take to see noticeable improvement?

Most users observe a reduction in lesion count after two to four weeks of consistent daily use, though individual response times may vary.

Is it safe to combine Persol AC 5% Gel with other acne medications?

It can be used alongside other topical agents, but avoiding simultaneous application of multiple active ingredients on the same spot is recommended to minimize irritation.

Does the gel cause sun sensitivity?

Benzoyl peroxide may increase photosensitivity in some individuals; therefore, sunscreen or protective clothing should be used when exposure to strong sunlight is expected.

Can I use the product if I have sensitive skin?

Individuals with sensitive skin should start with a smaller amount and gradually increase frequency to assess tolerance, and they may consider using a moisturizer to mitigate dryness.